Coincidence of Aspergillus and Primary Lung Adenocarcinoma – a Case Report and Literature Review

Author(s) :

Miruna-Ioana Lazăr1, Ioana-Miruna Stanciu1, Claudiu Mihai Ciucureanu3, Cristina Mihaela Olaru1, Cornelia Nițipir2

1 Department of Paediatrics, Marie Sklodowska Curie Emergency Hospital for Children, Bucharest, Romania
2 Department of Oncology, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania
3 University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania

Corresponding author: Ioana-Miruna Stanciu, Email:

Published: IiI, 2, 1 October 2023, 63 - 70 DOI: 10.53011/JMRO.2023.02.08

Open Access

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October 1, 2023 0 Comments


Although infrequent, lung cancer can be disguised by the synchronous presence of a fungal infection, most notably by the Aspergillus species. Some cases of incidental adenocarcinoma diagnosed during surgical treatment of pulmonary aspergillosis have been reported, showing just how these fungi can hide more serious, underlying pathology.

This review aims to raise awareness about this occurrence to accelerate the correct etiological diagnosis, establish a timely oncological treatment, and improve the overall morbidity and mortality in lung cancer patients. In addition, we present a rather alluring case of concurrent adenocarcinoma and Aspergillus infection to display how these two entities can appear together.


Figure 1. Chest X-ray on admission showed a hyper-transparent circumscribed lesion with a thick, anfractuous contour adjacent to the right pulmonary hilum.
Figure 2. CT scan of the chest showing a cavitary lesion within the lower right lobe surrounded by ground-glass opacities.
Figure 3. CT scan depicting the evolution of the cavitary lesion after exactly three months of systemic antibiotic therapy.
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