Author(s) :
Tiberiu Popescu1, Angelica Chiorean2, 3, Noemi Schultes4, Catalin Iacob1, Dan Eniu5, 6
1 Department of Radiation Oncology, RTC Amethyst, Cluj, Romania
2 Department of Imaging and Radiology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj, Romania
3 MedImages Clinic, Cluj, Romania
4 Department of Medical Physics, RTC Amethyst, Cluj, Romania
5 Department of Surgical Oncology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj, Romania
6 Department of Surgical Oncology, Prof. Dr. Ion Chiricuta Institute of Oncology, Cluj, Romania
Corresponding author: Tiberiu Popescu, Email: tiberiu.popescu@amethyst-radiotherapy.com
Publication History: Received - , Revised - , Accepted - , Published Online - .
Copyright: © The author(s). Published by Casa Cărții de Știință.
User License: Creative Commons Attribution – NonCommercial (CC BY-NC)
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Abstract
Stereotactic body radiation therapy (SBRT) is a type of radiotherapy which uses a high radiation dose delivered in a single or a few fractions and is employed with local curative intent for early-stage cancer, relapsed cancer or in the oligometastatic setting. The aim of this case report is to illustrate the potential of this technique in the salvage re-irradiation of a late isolated in field regional relapse after bilateral breast cancer.
This is the case of a 65-years-old woman with a metachronous bilateral breast cancer (left side-1998, stage IIB, Luminal type; right side-2010, stage IIA, Her2 positive) who received both chemo- and endocrine systemic therapy, underwent surgery and was irradiated on both sides, with a late solitary recurrence in her left internal mammary node chain (2018) treated by SBRT re-irradiation (40 Gy in 5 fractions). Three years after salvage SBRT, under Palbociclib+Letrozole and thorough follow-up protocol, she is still in clinical complete remission, with a normal CA 15-3 and metabolically inactive residual mass on PET-CT, negative on a recent biopsy.
SBRT is becoming a hallmark of oligometastatic disease management and can be invaluable in patients subjected to prior radiotherapy.
