Treatment approach for intraorbital metastasis with origin in breast cancer: case report
Publication Date : 20/10/2022
Breast cancer is the most common diagnosed cancer worldwide and although well-known its impressive characteristic to metastasize everywhere, orbital spreads are considered an exceptional event. We present a case of a 53-year-old patient initially diagnosed with luminal B cT4cN1M1 breast cancer (M1PUL, M1OSS) and received palliative chemotherapy, zoledronic acid and hormonotherapy without any major benefits (progressive disease). Two years later, the patient experienced right eye proptosis, local pain and decreasing visual acuity; CT (computed tomography) followed by MRI (magnetic resonance imaging) showed a soft tissue mass in the right orbit, along the right optic nerve but without invading it. A multidisciplinary team decided that the next therapeutical step should be orbital palliative radiotherapy. Taking into consideration the location of the metastasis and the high risk of imminent vision loss, stereotactic body radiation therapy (SBRT) was conducted. Two months after palliative SBRT, the proptosis and the local pain were resolved and an imaging partial response was obtained.
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