SECOND, PECULIAR RECURRENCE OF A WILMS TUMOUR- PLEURAL AND LATE
Publication Date : 20/10/2022
We present the case of a 2-year-old boy diagnosed in 2010 with intermediate risk, regressive type Nephroblastoma in the left kidney. He was treated with neoadjuvant chemotherapy followed by surgery and chemotherapy (SIOP protocol). After 11 months the cancer recurred in the left lung, so the patient was (re)classified as high risk and treated with 7C of chemotherapy. After 9 disease-free years, the periodic CT scan showed a 10/5cm tumour in the left lung, arising from the pleura. The tumour was completely resected, and pathology confirmed the nephroblastoma recurrence. The patient was further treated according to the UMBRELLA protocol (BB group) with chemotherapy and local irradiation. The tumour bed was irradiated with 25.2 Gy/14 fr, using Helical Tomotherapy. Following irradiation, the patient underwent high-dose chemotherapy and autologous stem-cell transplantation. The last clinical examination showed no signs of recurrence or severe toxicities and a good overall status of the patient.
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